It's a rainy night in Manhattan and not a creature is stirring except for ... Ben Grimm. When an intruder suddenly appears inside the Baxter Building, the Fantastic Four -- Mister Fantastic (Reed Richards), the Invisible Woman (Susan Storm Richards), the Human Torch (Johnny Storm), and the Thing (Ben Grimm) -- find themselves surrounded by a swarm of invading parasites. These carrion creatures composed of Negative Energy come to Earth using a human...

While Reed Richards attempts to save the inhabitants of Nu-World, Sue Richards mediates between a lost tribe of Old Atlantis and Prince Namor, and Johnny Storm and Ben Grimm are the last defense against the new Annihilation Wave.

"Drawn from Earth across the stars, the Marvel Universe's greatest villains and heroes are set against one another by the mysterious and unbelievably powerful Beyonder, with the winner promised the ultimate prize. But as battle lines are drawn, new alliances forged and old enemies clash, one among them is not willing to settle for anything less than godhood. Can even the combined might of the Avengers, Spider-Man, the Fantastic Four and the X-Men...

The struggle for ultimate power over the universe continues when a stockpile of evil twins overwhelm our superheroes. After Adam Warlock's return in Infinity gauntlet, his worse half, Magnus, wasn't far behind. The struggle for ultimate power over the universe continues when a stockpile of evil twins overwhelms the Fantastic Four, the Avengers, the X-Men, and New Warriors, and Alpha Flight.

Join the Fantastic Four in this collection of all-new adventures. Featuring Madame Masque, the Incredible Hulk and Galactus!